
Folic acid is a wat'∞¥×er-soluble vitamin, also known as vitamin B β9. In the folic acid m♥ ∏etabolism pathway, single nu☆Ωγcleotide polymorphisms (SNPs) of methylenetetra±♦hydrofolate reductase (MTHFR) and methionine synt<&™hetase (MTRR) can affect the activity ₽®↓of MTHFR and MTRR enzyme λφs and can affect Serum f↓επ'olate and homocysteine levels.&©Ω£γnbsp;It will lead to hypofolateemia a£≈↓∞nd hyperhomopenic acidemia, theγ™'reby increasing the risk of neonatal Ω∑birth defects, neural tube diseas≈↔÷es and cardiovascula§∞↓r diseases.
Folic acid gene testing can provide g ★uidance for people who lack☆Ω folic acid due to genetic fa↑©ctors to achieve precise medication; pr♦©Ω↔ovide the basis for the onset of pati↔ ents with hyperhomocysteinemia; define famil∑¥y genetic history, and provide guidance ∞ for eugenics and personaliz♦£≠∞ed medication.
Date:2020-03-26
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